mef a/e

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macrolide efflux pump

NCBI Pathogen Isolates

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UniProt

Protein entries specific to mef a/e

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Validation StatusCandidate

Overview

Validation Method: PCR detection
Drug Classes: erythromycin
Organisms: Group B Streptococcus
Geographic Location: Brazil
Papers: 1
Databases: Reslit

Papers1

Genetic diversity and antimicrobial resistance of invasive, noninvasive and colonizing group B Streptococcus isolates in southern Brazil.

PMID 36004365 · 2022

The study identified the presence of macrolide resistance genes mef A/E, erm B, and erm A/TR in Group B Streptococcus (GBS) isolates, with serotype V being strongly associated with erythromycin resistance. The most common genotypes were Ia/MT12 and V/MT18, showing high resistance to macrolides.

Gene Information

Gene Name: mef a/e
Allele: mef A/E
Encodes: macrolide efflux pump
Source Database: Reslit
Confers Resistance To: erythromycin
Organisms Tested In: • Group B Streptococcus
Geographic Location: Brazil
Validation Method: PCR detection

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mef a/e

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mef a/e

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