Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
efflux pump
Overview
Simultaneous detection of nine antibiotic resistance-related genes in Streptococcus agalactiae using multiplex PCR and reverse line blot hybridization assay.
The study developed a multiplex PCR and reverse line blot hybridization assay to detect nine antibiotic resistance-related genes in Streptococcus agalactiae, including erm(B), erm(A/TR), mef(A/E), tet(M), tet(O), aphA-3, aad-6, int-Tn, and mreA. These genes were found to be associated with resistance to macrolides, lincosamides, streptogramin B, tetracyclines, and aminoglycosides.
Genetic resistance elements carrying mef subclasses other than mef (A) in Streptococcus pyogenes
The study identifies various mef subclasses (mef(E), mef(I), mef(A/E), and a novel mef) associated with resistance genes (tet(M), tet(O), and catQ) in Streptococcus pyogenes, highlighting the diversity of genetic elements involved in macrolide and tetracycline resistance.
Antimicrobial activity, antibiotic susceptibility and virulence factors of Lactic Acid Bacteria of aquatic origin intended for use as probiotics in aquaculture.
The study identified the erythromycin resistance gene mef(A/E) in Pediococcus pentosaceus and Weissella cibaria, and the lincosamide resistance gene lnu(A) in Pediococcus pentosaceus.
Nasopharyngeal carriage, serotype distribution and antimicrobial resistance of Streptococcus pneumoniae among children from Brazil before the introduction of the 10-valent conjugate vaccine.
The study identified erythromycin resistance genes mef(A/E) and erm(B) in Streptococcus pneumoniae isolates, with the former being associated with the M phenotype. Penicillin non-susceptibility was linked to specific serotypes such as 14 and 23F.
In vitro activity of solithromycin against erythromycin-resistant Streptococcus agalactiae.
Solithromycin showed potent activity against erythromycin-resistant Streptococcus agalactiae, with MIC 50 and MIC 90 values of 0.03 μg/ml and 0.125 μg/ml, respectively. The study identified erm(B) and mef(A/E) as the primary resistance mechanisms.
High Prevalence of Macrolide-resistance and Molecular Characterization of Streptococcus pyogenes Isolates Circulating in China from 2009 to 2016.
The study identified high prevalence of macrolide resistance in Streptococcus pyogenes isolates in China, with erm(B) and mef(A/E) genes being the primary mechanisms. Tet(M) was the main determinant of tetracycline resistance, and mutations in gyrA and parC were associated with fluoroquinolone resistance.
Microbiological and clinical characteristics of Streptococcus gallolyticus subsp. pasteurianus infection in China.
The study characterizes the AMR genes and mutations in Streptococcus gallolyticus subsp. pasteurianus isolates from China, identifying erm(B), erm(A), erm(T), mef(A/E), tet(L), tet(O), and tet(M) as major contributors to erythromycin, clindamycin, and tetracycline resistance.
Prevalence of Various Vaccine Candidate Proteins in Clinical Isolates of Streptococcus pneumoniae: Characterization of the Novel Pht Fusion Proteins PhtA/B and PhtA/D.
The study identified the prevalence of various vaccine candidate proteins in clinical isolates of Streptococcus pneumoniae, including the novel Pht fusion proteins PhtA/B and PhtA/D. It also characterized resistance mechanisms such as erm(B), mef(A/E), tet(M), and mutations in pbp1a, pbp2x, and pbp2b contributing to macrolide, tetracycline, and penicillin resistance.
Increase of Macrolide-Resistance in Streptococcus pneumoniae Strains After the Introduction of the 13-Valent Pneumococcal Conjugate Vaccine in Lima, Peru.
The study found a significant increase in macrolide resistance in Streptococcus pneumoniae strains after the introduction of the 13-valent pneumococcal conjugate vaccine (PCV13) in Lima, Peru. The primary resistance mechanisms identified were the erm(B) gene and the mef(A/E) gene.
Baseline azithromycin resistance in the gut microbiota of preterm born infants.
The study identifies the presence of macrolide resistance genes in the gut microbiota of preterm infants, with erm(C) and msr(A) being the most common. These genes were found in various bacterial genera, including Staphylococcus and Enterococcus.
Streptococcus suis Research Update: Serotype Prevalence and Antimicrobial Resistance Distribution in Swine Isolates Recovered in Spain from 2020 to 2022.
The study identified the prevalence of antimicrobial resistance genes in Streptococcus suis isolates from Spain, including tet(O), erm(B), lnu(B), lsa(E), tet(M), and mef(A/E). High resistance levels were observed for clindamycin, chlortetracycline, and sulfadimethoxine.
The gut microbiota of wild birds undergoing rehabilitation as a reservoir of multidrug-resistant enterococci in a metropolitan area in Brazil.
The study identified multiple antimicrobial resistance genes in enterococci isolated from wild birds, including genes conferring resistance to aminoglycosides, erythromycin, tetracycline, and streptogramins.
Efflux-Mediated Macrolide Resistance in Clinical Streptococcus Isolates: A Comparative Molecular Study.
The study identified mef(A/E) as the dominant efflux-mediated macrolide resistance gene in UAE Streptococcus isolates, with functional validation of its efflux activity. msr(D) was also detected but at a lower frequency. No tet(K) was found.
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