menD

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2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase

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Protein entries specific to menD

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Validation StatusCandidate

Overview

Validation Method: functional verification via immunoblotting and gene cloning
Drug Classes: gentamicin
Organisms: Staphylococcus aureus
Papers: 1
Databases: Reslit

Papers1

A functional menadione biosynthesis pathway is required for capsule production by Staphylococcus aureus.

PMID 34825882 · 2021

The study identifies menD as a gene involved in capsule production in Staphylococcus aureus, with polymorphisms in menD associated with increased resistance to gentamicin.

Gene Information

Gene Name: menD
Allele: menD
Encodes: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase
Source Database: Reslit
Confers Resistance To: gentamicin
Organisms Tested In: • Staphylococcus aureus
Validation Method: functional verification via immunoblotting and gene cloning

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menD

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menD

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