The study identifies eight distinct resistance gene classes from the environmental resistome of albicidin, including AraC family proteins, HlyD family transporters, RecA recombinases, hydrolases, a MerR family protein, a pentapeptide repeat protein, a glutathione S-transferase-like protein, and a monooxygenase. These genes confer varying levels of resistance to albicidin through mechanisms such as efflux, degradation, sequestration, and modification.