mex c

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efflux pump

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

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UniProt

Protein entries specific to mex c

AMR Rules

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Validation StatusCandidate

Overview

Validation Method: real-time RT-PCR
Drug Classes: fluoroquinolones, aminoglycosides, tetracycline
Organisms: Pseudomonas aeruginosa
Geographic Location: Romania
Papers: 1
Databases: Reslit

Papers1

Uncovering the Resistance Mechanisms in Extended-Drug-Resistant Pseudomonas aeruginosa Clinical Isolates: Insights from Gene Expression and Phenotypic Tests.

PMID 37764055 · 2023

The study identified bla GES-2, bla OXA48-like, bla NDM, bla SPM, and bla VIM as the main carbapenemase genes in MDR P. aeruginosa isolates. Overexpression of mex efflux pumps, particularly mex C, was strongly associated with multidrug resistance.

Gene Information

Gene Name: mex c
Allele: mex C
Encodes: efflux pump
Source Database: Reslit
Confers Resistance To: fluoroquinolonesaminoglycosidestetracycline
Organisms Tested In: • Pseudomonas aeruginosa
Geographic Location: Romania
Validation Method: real-time RT-PCR

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mex c

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mex c

Gene Information