mexvw

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efflux pump

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to mexvw

AMR Rules

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Validation StatusCandidate

Overview

Validation Method: mutational analysis and MIC testing
Drug Classes: fluoroquinolones, tetracycline, phenicols, trimethoprim
Organisms: Pseudomonas paraeruginosa
Geographic Location: Argentina|Canada|Germany|United States
Papers: 1
Databases: Reslit

Papers1

Comparative genomics of Pseudomonas paraeruginosa.

PMID 40709931 · 2025

The study identifies various AMR genes and mutations in Pseudomonas paraeruginosa, including carbapenemases like blaVIM-2, blaVIM-6, blaVIM-28, and blaKPC-2, as well as efflux pump genes (mexAB-oprM, mexCD-oprJ, etc.), and mutations in oprD, mexS, mexR, mexZ, lasR, mvfR, and vqsM that contribute to antibiotic resistance.

Gene Information

Gene Name: mexvw
Allele: mexVW
Encodes: efflux pump
Source Database: Reslit
Confers Resistance To: fluoroquinolonestetracyclinephenicolstrimethoprim
Organisms Tested In: • Pseudomonas paraeruginosa
Geographic Location: Argentina|Canada|Germany|United States
Validation Method: mutational analysis and MIC testing
Sequence Accession: CP000744|JAOYTE010000034|JAPHNP010000117|NZ_JAPHNN010000169|LLLP01000037|LLNU01000093|RXTD01000086|RXTL01000080|DAFOAA010000053|DAFSFU010000036|DAFQBL010000010|JAWLON010000026|DAHOAI010000026|NZ_CP027170|NZ_CP029094|CP109657|JAOYTE00000000|JAPHNN00000000|JAPHNO00000000|JAPHNP00000000|JAOWAL00000000

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mexvw

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mexvw

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