mexyz

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efflux pump

NCBI Pathogen Isolates

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UniProt

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AMR Rules

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Validation StatusCandidate

Overview

Validation Method: genomic sequencing
Drug Classes: carbapenems, fluoroquinolones, macrolides
Organisms: Pseudomonas aeruginosa
Geographic Location: Australia
Papers: 1
Databases: Reslit

Papers1

Clinically Relevant Concentrations of Polymyxin B and Meropenem Synergistically Kill Multidrug-Resistant Pseudomonas aeruginosa and Minimize Biofilm Formation.

PMID 33918040 · 2021

The study identifies several AMR genes and mutations in multidrug-resistant Pseudomonas aeruginosa strains, including beta-lactamases, efflux pumps, and mutations in the pmrAB system, which contribute to resistance against polymyxins and other antibiotics.

Gene Information

Gene Name: mexyz
Allele: mexYZ
Encodes: efflux pump
Source Database: Reslit
Confers Resistance To: carbapenemsfluoroquinolonesmacrolides
Organisms Tested In: • Pseudomonas aeruginosa
Geographic Location: Australia
Validation Method: genomic sequencing
Sequence Accession: PRJNA664899

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mexyz

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mexyz

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