mgtA

mgt macrolide glycotransferase

Validation StatusConfirmed2+ DBs

Overview

Mechanism: antibiotic inactivation
Validation Method: genome sequencing and functional analysis
Drug Classes: macrolides, polymyxin b
Organisms: Streptomyces lividans, Renibacterium salmoninarum, Salmonella enterica serovar Typhimurium
Papers: 2
Databases: Card DatabaseReslit

Papers2

Gene Information

Gene Name: mgtA
Allele: mgtA
Encodes: mgt macrolide glycotransferase
Source Database: Card Database
Mechanism: antibiotic inactivation
Organisms Tested In: • Streptomyces lividans
Sequence Accession: DQ185434.2
Protein Accession: ABA28305.2
Notes: ARO:3000462

Genome sequence of the fish pathogen Renibacterium salmoninarum suggests reductive evolution away from an environmental Arthrobacter ancestor.

PMID 18723615 · 2008

The genome of Renibacterium salmoninarum was sequenced, revealing the presence of a beta-lactamase gene (bla) that confers resistance to beta-lactam antibiotics.

Gene Information

Gene Name: mgtA
Allele: mgtA
Encodes: macrolide glycosyltransferase
Source Database: Reslit
Confers Resistance To: macrolides
Organisms Tested In: • Renibacterium salmoninarum
Validation Method: genome sequencing and functional analysis
Sequence Accession: NC_010168|CP000910

Signal-specific temporal response by the Salmonella PhoP/PhoQ regulatory system.

PMID 24256574 · 2014

The study identifies mgtA, pmrD, and ugtL as genes involved in Salmonella's resistance to polymyxin B through the PhoP/PhoQ regulatory system.

Gene Information

Gene Name: mgtA
Allele: mgtA
Encodes: Mg2+ transporter
Source Database: Reslit
Confers Resistance To: polymyxin b
Organisms Tested In: • Salmonella enterica serovar Typhimurium
Validation Method: expression analysis and survival assay

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mgtA

mgt macrolide glycotransferase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to mgtA

AMR Rules

Browse AMR rules for mgtA

Validation StatusConfirmed2+ DBs

Overview

Mechanism: antibiotic inactivation
Validation Method: genome sequencing and functional analysis
Drug Classes: macrolides, polymyxin b
Organisms: Streptomyces lividans, Renibacterium salmoninarum, Salmonella enterica serovar Typhimurium
Papers: 2
Databases: Card DatabaseReslit

Papers2

PMID N/A

Gene Information

Gene Name: mgtA
Allele: mgtA
Encodes: mgt macrolide glycotransferase
Source Database: Card Database
Mechanism: antibiotic inactivation
Organisms Tested In: • Streptomyces lividans
Sequence Accession: DQ185434.2
Protein Accession: ABA28305.2
Notes: ARO:3000462

Genome sequence of the fish pathogen Renibacterium salmoninarum suggests reductive evolution away from an environmental Arthrobacter ancestor.

PMID 18723615 · 2008

The genome of Renibacterium salmoninarum was sequenced, revealing the presence of a beta-lactamase gene (bla) that confers resistance to beta-lactam antibiotics.

Gene Information

Gene Name: mgtA
Allele: mgtA
Encodes: macrolide glycosyltransferase
Source Database: Reslit
Confers Resistance To: macrolides
Organisms Tested In: • Renibacterium salmoninarum
Validation Method: genome sequencing and functional analysis
Sequence Accession: NC_010168|CP000910

Signal-specific temporal response by the Salmonella PhoP/PhoQ regulatory system.

PMID 24256574 · 2014

The study identifies mgtA, pmrD, and ugtL as genes involved in Salmonella's resistance to polymyxin B through the PhoP/PhoQ regulatory system.

Gene Information

Gene Name: mgtA
Allele: mgtA
Encodes: Mg2+ transporter
Source Database: Reslit
Confers Resistance To: polymyxin b
Organisms Tested In: • Salmonella enterica serovar Typhimurium
Validation Method: expression analysis and survival assay

Comments (0)

No comments yet. Be the first to comment!

mgtA

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mgtA

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