mipB

View on PubMed

membrane-associated sensor for polymyxin

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to mipB

AMR Rules

Browse AMR rules for mipB

Validation StatusCandidate

Overview

Mechanism: mutation
Validation Method: association with MICs
Drug Classes: polymyxin b, colistin, polymyxin b|colistin
Organisms: Pseudomonas aeruginosa
Geographic Location: Australia|India
Papers: 1
Databases: Reslit
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
V469M	-	-	Pseudomonas aeruginosa	polymyxin b\|colistin	Reslit	Candidate

Papers1

Detection of Genes Associated with Polymyxin and Antimicrobial Peptide Resistance in Isolates of Pseudomonas aeruginosa.

PMID 41226536 · 2025

The study identified SNPs in mipB, pmrB, and mprF associated with increased resistance to polymyxin B, colistin, LL-37, and Mel4 in Pseudomonas aeruginosa isolates.

Gene Information

Gene Name: mipB
Allele: mipB
Encodes: membrane-associated sensor for polymyxin
Source Database: Reslit
Mechanism: mutation
Confers Resistance To: polymyxin bcolistin
Organisms Tested In: • Pseudomonas aeruginosa
Geographic Location: Australia|India
Validation Method: association with MICs
Sequence Accession: PRJNA590804|PRJNA431326|SAMN01918025|SAMN12437401

Comments (0)

No comments yet. Be the first to comment!

mipB

Mutations

Gene Information

Browse AMR Genes

mipB

Mutations

Gene Information