misR

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response regulator

NCBI Pathogen Isolates

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NCBI Reference Gene Catalog

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UniProt

Protein entries specific to misR

AMR Rules

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Validation StatusCandidate

Overview

Validation Method: MIC assays, MBC assays, Western blotting, RNA-Seq analysis
Drug Classes: aminoglycosides
Organisms: Neisseria gonorrhoeae
Papers: 1
Databases: Reslit

Papers1

The MisR Response Regulator Is Necessary for Intrinsic Cationic Antimicrobial Peptide and Aminoglycoside Resistance in Neisseria gonorrhoeae.

PMID 27216061 · 2016

The MisR response regulator is essential for intrinsic resistance to cationic antimicrobial peptides and aminoglycosides in Neisseria gonorrhoeae. Loss of MisR increases susceptibility to these antimicrobials and affects membrane permeability.

Gene Information

Gene Name: misR
Allele: misR
Encodes: response regulator
Source Database: Reslit
Confers Resistance To: aminoglycosides
Organisms Tested In: • Neisseria gonorrhoeae
Validation Method: MIC assays, MBC assays, Western blotting, RNA-Seq analysis

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misR

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misR

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