Browse AMR Genes

Explore antimicrobial resistance genes from the literature

mmpL4

Putative membrane protein

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to mmpL4

Browse AMR rules for mmpL4

Overview

Drug Classes: clarithromycin
Organisms: Mycobacterium abscessus
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
P726L	-	-	Mycobacterium abscessus	clarithromycin	Reslit	Candidate

Papers1

1

Evolution of Mycobacterium abscessus in the human lung: Cumulative mutations and genomic rearrangement of porin genes in patient isolates.

PMID 37221835 · 2023

Mutation in mmpL4 gene associated with clarithromycin resistance in patient 1S

Mutation Information

Protein Change: P726L
Organisms: Mycobacterium abscessus
Confers Resistance To: clarithromycin
Validation Method: non-synonymous SNP analysis
Source Database: Reslit