mmpL9

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efflux pump

NCBI Pathogen Isolates

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UniProt

Protein entries specific to mmpL9

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Validation StatusCandidate

Overview

Validation Method: quantitative real-time PCR (qRT-PCR) showing increased transcriptional levels
Drug Classes: linezolid
Organisms: Mycobacterium abscessus
Geographic Location: Shanghai
Papers: 1
Databases: Reslit

Papers1

Molecular Analysis of Linezolid-Resistant Clinical Isolates of Mycobacterium abscessus.

PMID 30478161 · 2019

The study identifies lmrS and mmpL9 efflux pumps as playing a major role in linezolid resistance in Mycobacterium abscessus, alongside 24 newly identified genes potentially involved in resistance mechanisms.

Gene Information

Gene Name: mmpL9
Allele: mmpL9
Encodes: efflux pump
Source Database: Reslit
Confers Resistance To: linezolid
Organisms Tested In: • Mycobacterium abscessus
Geographic Location: Shanghai
Validation Method: quantitative real-time PCR (qRT-PCR) showing increased transcriptional levels
Sequence Accession: PRJNA488058

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mmpL9

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mmpL9

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