Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
efflux pump
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| mmr | Reslit | 2 | ethidium bromide, erythromycin | Mycobacterium tuberculosis | - | 2012, 2013 | - | - |
| Mmr | Reslit | 1 | ciprofloxacin | Mycobacterium tuberculosis | - | 2022 | - | - |
Role of the Mmr efflux pump in drug resistance in Mycobacterium tuberculosis.
The Mmr efflux pump in Mycobacterium tuberculosis was found to contribute to resistance against ethidium bromide, tetraphenylphosphonium, safranin O, and cetyltrimethylammonium bromide. However, it did not significantly affect isoniazid resistance.
The role of transport mechanisms in mycobacterium tuberculosis drug resistance and tolerance.
The paper discusses the role of transport mechanisms, particularly efflux pumps, in Mycobacterium tuberculosis drug resistance and tolerance, highlighting the importance of efflux pump activity in reducing drug susceptibility.
The resistance mechanisms of bacteria against ciprofloxacin and new approaches for enhancing the efficacy of this antibiotic.
The paper discusses the resistance mechanisms of bacteria against ciprofloxacin, focusing on mutations in target enzymes like gyrA and parC, plasmid-mediated resistance genes such as qnr, aac(6')-Ib-cr, oqxAB, and qepA, and efflux pumps contributing to resistance.
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