mnmG

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tRNA modification enzyme

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to mnmG

AMR Rules

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Validation StatusCandidate

Overview

Validation Method: gene knockout and expression analysis
Drug Classes: ciprofloxacin
Organisms: Escherichia coli
Papers: 1
Databases: Reslit

Papers1

Genome Recombination-Mediated tRNA Up-Regulation Conducts General Antibiotic Resistance of Bacteria at Early Stage.

PMID 35126332 · 2021

The study shows that tRNA up-regulation mediated by genome recombination contributes to early-stage antibiotic resistance in Escherichia coli, particularly under ciprofloxacin stress.

Gene Information

Gene Name: mnmG
Allele: mnmG
Encodes: tRNA modification enzyme
Source Database: Reslit
Confers Resistance To: ciprofloxacin
Organisms Tested In: • Escherichia coli
Validation Method: gene knockout and expression analysis

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mnmG

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mnmG

Gene Information