Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
macrolide phosphotransferase (MPH)
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| mphK | Card Database | 1 | - | Bacillus subtilis subsp. subtilis | - | - | CP010314.1 | AJE92936.1 |
| mph(K) | ResFinder DatabaseReslit | 3 | macrolides, TELITHROMYCIN +1 | Escherichia coli +2 | Egypt, USA|Peru|Egypt|Cambodia|Kenya | 2013, 2018, 2020 | 964 | - |
| MphK | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 4 | erythromycin, TELITHROMYCIN +2 | Vibrio cholerae O1 El Tor +1 | China | 2016, 2018 | KT151654|KT151655|KT151656|KT151657|KT151658|KT151659|KT151660|KT151661|KT151662|KT151663|KT151664 | AJE92936.1 |
Molecular characterization of multidrug resistant hospital isolates using the antimicrobial resistance determinant microarray.
The study characterized various AMR genes in multidrug-resistant hospital isolates using the Antimicrobial Resistance Determinant Microarray (ARDM). Key findings include the detection of beta-lactamase genes (bla TEM, bla SHV, bla CTX-M, bla OXA), aminoglycoside resistance genes (aadA1, aadA2, aph3'/str(A), aph6/str(B), aac(3)-III, aac(6')-Ib), tetracycline resistance genes (tet(A), tet(B), tet(D), tet(39)), sulfonamide resistance genes (sulI, sulII), trimethoprim resistance genes (dfrA1, dfrA10, dfrA14, dfrA17), quaternary amine resistance gene (qacEΔ1), chloramphenicol resistance genes (catA1, cat4), and glycopeptide resistance genes (vanB, vanB2).
Variations in SXT elements in epidemic Vibrio cholerae O1 El Tor strains in China.
The study identifies various antibiotic resistance genes within SXT elements in epidemic Vibrio cholerae O1 El Tor strains in China, highlighting their role in multidrug resistance.
The evolution of substrate discrimination in macrolide antibiotic resistance enzymes.
The evolution of substrate discrimination in macrolide antibiotic resistance enzymes.
The evolution of substrate discrimination in macrolide antibiotic resistance enzymes.
The evolution of substrate discrimination in macrolide antibiotic resistance enzymes.
Tracking Antimicrobial Resistance Determinants in Diarrheal Pathogens: A Cross-Institutional Pilot Study.
The study identified 55 different antimicrobial resistance determinants in diarrheal pathogens, highlighting the presence of genes conferring resistance to multiple antibiotic classes, including beta-lactams, aminoglycosides, macrolides, tetracyclines, phenicols, sulfonamides, and others. Notably, carbapenemase genes like bla OXA-48 and bla NDM were detected in certain isolates, indicating emerging resistance concerns.
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