mphbm

View on PubMed

macrolide phosphotransferase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to mphbm

AMR Rules

Browse AMR rules for mphbm

Validation StatusCandidate

Overview

Mechanism: phosphorylation of erythromycin
Validation Method: cloning in E. coli and determination of MIC
Drug Classes: erythromycin
Organisms: Escherichia coli, Stenotrophomonas maltophilia
Papers: 1
Databases: Reslit

Papers1

Stenotrophomonas maltophilia D457R contains a cluster of genes from gram-positive bacteria involved in antibiotic and heavy metal resistance.

PMID 10858330 · 2000

The study identified the mphBM gene, which confers erythromycin resistance, and the cadA gene, which confers cadmium resistance, in Stenotrophomonas maltophilia D457R. Both genes were experimentally validated.

Gene Information

Gene Name: mphbm
Allele: mphBM
Encodes: macrolide phosphotransferase
Source Database: Reslit
Mechanism: phosphorylation of erythromycin
Confers Resistance To: erythromycin
Organisms Tested In: • Escherichia coli
• Stenotrophomonas maltophilia
Validation Method: cloning in E. coli and determination of MIC
Sequence Accession: AJ251015

Comments (0)

No comments yet. Be the first to comment!

mphbm

Gene Information

Browse AMR Genes

mphbm

Gene Information