Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
UDP-N-acetylmuramate--alanine ligase
Overview
Comprehensive identification of single nucleotide polymorphisms associated with beta-lactam resistance within pneumococcal mosaic genes.
The study identifies 51 loci, including 301 SNPs, associated with beta-lactam non-susceptibility in Streptococcus pneumoniae, focusing on genes involved in peptidoglycan biosynthesis and other pathways.
Deciphering the distance to antibiotic resistance for the pneumococcus using genome sequencing data.
The study identifies numerous genes and mutations associated with antibiotic resistance in Streptococcus pneumoniae through genome-wide association studies, highlighting the genetic basis of resistance to penicillin, trimethoprim, cotrimoxazole, erythromycin, and fluoroquinolones.
Antimicrobial Peptide Exposure Selects for Resistant and Fit Stenotrophomonas maltophilia Mutants That Show Cross-Resistance to Antibiotics.
The study identifies mutations in genes such as mraW, smd_0008, sspb, lptB, wbiI, ftsW, sodB, phoQ, and crp that confer resistance to antimicrobial peptides (AMPs) LL-37, PR-39, and colistin in Stenotrophomonas maltophilia. These mutations lead to cross-resistance to antibiotics and highlight the rapid development of AMP resistance in this opportunistic pathogen.
No comments yet. Be the first to comment!