Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
Penicillin binding protein 2
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| mrdA | Reslit | 2 | beta lactams, carbapenems | Escherichia coli | Alaska | 2018, 2023 | SRP126755 | - |
| MrdA | Reslit | 1 | beta lactams | Escherichia coli | - | 2022 | - | - |
Acquisition and dissemination of cephalosporin-resistant E. coli in migratory birds sampled at an Alaska landfill as inferred through genomic analysis.
The study identified various beta-lactam resistance genes, including bla CTX-M-55, bla CTX-M-14, and bla CMY-2, in cephalosporin-resistant E. coli isolates from gulls and bald eagles in Alaska. These genes were found to confer resistance to beta-lactam antibiotics.
Essential Paralogous Proteins as Potential Antibiotic Multitargets in Escherichia coli.
The study identifies essential paralogous proteins in E. coli that could serve as multitargets for antibiotics, focusing on clinically validated targets like DNA gyrase, topoisomerase IV, and penicillin-binding proteins, as well as novel potential targets without human homologs.
Uropathogenic Escherichia coli (UPEC)-Associated Urinary Tract Infections: The Molecular Basis for Challenges to Effective Treatment.
This review discusses the molecular basis of challenges to effective treatment of UPEC-associated urinary tract infections, focusing on virulence factors and antibiotic resistance mechanisms.
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