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mscM

Mechanosensitive channel protein MscM

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to mscM

Browse AMR rules for mscM

Overview

Drug Classes: azithromycin|trimethoprim
Organisms: Escherichia coli
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
-	G361A	-	Escherichia coli	azithromycin\|trimethoprim	Reslit	Candidate

Papers1

1

Compatibility of Evolutionary Responses to Constituent Antibiotics Drive Resistance Evolution to Drug Pairs.

PMID 33480997 · 2021

Mutations in mscM were observed in isolates evolved to azithromycin and trimethoprim.

Mutation Information

Nucleotide Change: G361A
Organisms: Escherichia coli
Confers Resistance To: azithromycin|trimethoprim
Validation Method: whole-genome sequencing and MIC testing
Source Database: Reslit