Browse AMR Genes

Explore antimicrobial resistance genes from the literature

mshC

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to mshC

Browse AMR rules for mshC

Overview

Mechanism: single resistance variant
Drug Classes: ethionamide, isoniazid
Organisms: Mycobacterium tuberculosis
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
A403G	-	single resistance variant	Mycobacterium tuberculosis	ethionamideisoniazid	Card Database	Candidate

Papers1

1

Integrating standardized whole genome sequence analysis with a global Mycobacterium tuberculosis antibiotic resistance knowledgebase.

PMID 30337678 · 2018

Mycobacterium tuberculosis mshC mutations conferring resistance to ethionamide; CARD accession: CARD:3004934

Mycobacterium tuberculosis mshC mutations conferring resistance to isoniazid; CARD accession: CARD:3004927

Mutation Information

Protein Change: A403G
Organisms: Mycobacterium tuberculosis
Confers Resistance To: ethionamideisoniazid
Effect on Function: single resistance variant
Source Database: Card Database