Browse AMR Genes

Explore antimicrobial resistance genes from the literature

msrDL

regulatory ORF

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to msrDL

Browse AMR rules for msrDL

Overview

Drug Classes: erythromycin
Papers: 1
Mutations: 3

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
-	A13G	-	-	erythromycin	Reslit	Candidate
-	T10A	-	-	erythromycin	Reslit	Candidate
-	T6A	-	-	erythromycin	Reslit	Candidate

Papers1

1

Regulation of the macrolide resistance ABC-F translation factor MsrD.

PMID 37393329 · 2023

Mutations in msrDL affect ribosome stalling and resistance to erythromycin.

Mutation Information

msrDL: c.A13G msrDL: c.T10A msrDL: c.T6A

Nucleotide Change: A13G, T10A, T6A
Confers Resistance To: erythromycin
Validation Method: mutagenesis and toeprinting assays
Source Database: Reslit