Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
peptide methionine sulfoxide reductase
Overview
DNA microarray-based identification of genes associated with glycopeptide resistance in Staphylococcus aureus.
The study identifies 17 genes associated with glycopeptide resistance in Staphylococcus aureus, including 8 novel genes. Overexpression of these genes, particularly graF and msrA2, significantly increases resistance to vancomycin, teicoplanin, and oxacillin.
Comparative proteomics-based identification of genes associated with glycopeptide resistance in clinically derived heterogeneous vancomycin-intermediate Staphylococcus aureus strains.
The study identified five differentially expressed proteins, including IsaA, MsrA2, Asp23, GpmA, and AhpC, which were up-regulated in hVISA strains. Increased expression of isaA was suggested to be related to hVISA resistance.
Network analysis of antimicrobial resistance in Staphylococcus aureus: characterization of hub genes and their functional implications.
The study identifies hub genes involved in antimicrobial resistance in Staphylococcus aureus, including mecA, fosB, arlR, mepA, mgrA, arlS, and msrA2, which are associated with mechanisms such as efflux pump regulation, target protection, and target replacement.
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