mstX

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mycothiol S-transferase

NCBI Pathogen Isolates

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NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to mstX

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Validation StatusCandidate

Overview

Mechanism: thiol transferase and peroxidase activity
Validation Method: MIC and growth curve inhibition assay, site-directed mutagenesis, enzymatic activity assays
Drug Classes: neomycin, vancomycin, gentamicin, lincomycin, azithromycin
Organisms: Corynebacterium glutamicum
Papers: 1
Databases: Reslit

Papers1

Characterization of Xi-class mycothiol S-transferase from Corynebacterium glutamicum and its protective effects in oxidative stress.

PMID 31655587 · 2019

The study characterizes the ncgl1216 gene, now named mstX, as a mycothiol S-transferase Xi class with thiol transferase and reductase activities, playing a critical role in oxidative stress resistance in Corynebacterium glutamicum.

Gene Information

Gene Name: mstX
Allele: mstX
Encodes: mycothiol S-transferase
Source Database: Reslit
Mechanism: thiol transferase and peroxidase activity
Confers Resistance To: neomycinvancomycingentamicinlincomycinazithromycin
Organisms Tested In: • Corynebacterium glutamicum
Validation Method: MIC and growth curve inhibition assay, site-directed mutagenesis, enzymatic activity assays

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mstX

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mstX

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