mtrF

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efflux pump

NCBI Pathogen Isolates

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NCBI Reference Gene Catalog

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UniProt

Protein entries specific to mtrF

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Validation StatusCandidate

Overview

Mechanism: efflux pump
Validation Method: expression in E. coli and MIC testing
Drug Classes: sulfonamides
Organisms: Neisseria gonorrhoeae, Escherichia coli
Papers: 1
Databases: Reslit

Papers1

Structure and function of Neisseria gonorrhoeae MtrF illuminates a class of antimetabolite efflux pumps.

PMID 25818299 · 2015

The study identifies MtrF as a sulfonamide efflux pump in Neisseria gonorrhoeae, demonstrating its role in reducing susceptibility to sulfonamide antimetabolites.

Gene Information

Gene Name: mtrF
Allele: mtrF
Encodes: efflux pump
Source Database: Reslit
Mechanism: efflux pump
Confers Resistance To: sulfonamides
Organisms Tested In: • Neisseria gonorrhoeae
• Escherichia coli
Validation Method: expression in E. coli and MIC testing

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mtrF

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mtrF

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