The study identifies mupA as a gene associated with high-level mupirocin resistance in multidrug-resistant methicillin-resistant Staphylococcus aureus (MDR MRSA).

The study identifies mupA as a plasmid-encoded gene responsible for high-level mupirocin resistance in Staphylococcus aureus isolates from children with recurrent skin and soft tissue infections.

The study characterizes various methicillin-resistant Staphylococcus aureus (MRSA) clones, highlighting their antimicrobial resistance and virulence-associated markers, with a focus on SCC mec types and PVL status.

The study identified various AMR genes in S. aureus strains from foods and food handlers, including blaZ, mupA, ermC, msrB, msrA, aacA, aphD, aadD, and tetK, which confer resistance to beta-lactams, mupirocin, erythromycin, clindamycin, aminoglycosides, and tetracycline.

The study identifies and characterizes novel SCCmec-SCCM1 composite islands in MRSA isolates, highlighting the presence of various AMR genes such as blaZ, erm(A), aadD, qacA, qacC, merA, merB, fosB, sdrM, aacA-aphD, far1 (fusB), Q6GD50 (fusC), and cat-pC194 (pMC524).

The study identified MRSA ST239-III isolates in Ohio, USA, which showed resistance to several antibiotics including clindamycin, moxifloxacin, gentamicin, tetracycline, and trimethoprim-sulfamethoxazole. The isolates did not possess virulent determinants such as PVL, TSST, ACME, or mupA.

The study identified mupA as the gene responsible for high-level mupirocin resistance and qacA/B as the genes responsible for chlorhexidine resistance in Staphylococcus aureus.

The study identified the presence of methicillin-resistant Staphylococcus aureus (MRSA) and high-level mupirocin-resistant strains in nasal swabs of emergency department patients using PCR/ESI-MS technology.

The study found a high prevalence of mupirocin resistance in Staphylococcus aureus isolates from a pediatric population, with 31.3% of isolates being resistant. The genes mupA and mupB were identified as conferring high-level mupirocin resistance.

The study identified the mupA gene as a cause of high-level mupirocin resistance in coagulase-negative staphylococci (CoNS) from nasal carriers of end-stage renal disease patients and hospital personnel.

The study identified mupA and qacA/B genes as markers for mupirocin and chlorhexidine resistance in MRSA strains isolated from NICU patients.

The study identified various AMR genes in MRSA isolates from Kuwait hospitals, including aphA3, aacA-aphD, ermA, ermC, mupA, tetK, tetM, fusC, far1, msrA, mphC, sat, qacA, qacC, merA, merB, dfrS1, aadD, fosB, cat, sdrM, icaA, icaC, and icaD, which conferred resistance to multiple antibiotics.

The study identified high-level mupirocin resistance (HLMR) due to the mupA gene and chlorhexidine resistance via qacA/B genes in methicillin-resistant staphylococcal isolates from a dialysis unit.

The study developed a multiplex PCR assay to detect genes associated with resistance to chlorhexidine, quaternary ammonium compounds, mupirocin, and methicillin, while also distinguishing Staphylococcus aureus from coagulase-negative staphylococci.

The study identified mupA and qacA/B genes associated with mupirocin and chlorhexidine resistance in USA300 MRSA isolates from military trainees.

The study identifies a Staphylococcus aureus clone resistant to mupirocin and fusidic acid, carrying exotoxin genes such as mupA, fusB, ermC, ermA, lukS/lukF-PV, eta, etb, and fnbA, which contribute to its pathogenicity and resistance mechanisms.

The study identified methicillin-resistant staphylococcal strains carrying the mecA gene, erythromycin resistance genes ermB and msrA/B, and mupirocin resistance gene mup. These genes conferred resistance to methicillin, erythromycin, clindamycin, and mupirocin.

The study identifies mupA as a gene conferring mupirocin resistance in Staphylococcus aureus in Africa, with varying prevalence rates across different countries.

The study identified mupA, norA, smr, and qacA/B genes as prevalent in MRSA isolates, with mupA showing high prevalence in high-level mupirocin-resistant strains. No vanA gene was detected in vancomycin-resistant strains.

The study identified mupA as a gene associated with high-level mupirocin resistance (HLMR) in Staphylococcus aureus isolates, while mupB was not detected in any HLMR isolates.

The paper discusses the mechanisms of antibiotic resistance in Staphylococcus aureus, focusing on beta-lactam resistance through the blaZ and mecA genes, glycopeptide resistance via the vanA operon, and resistance to other antibiotics through various genes and mutations.

The study identified various AMR genes in MRSA isolates from Iranian ICUs, including genes conferring resistance to aminoglycosides, macrolides, tetracycline, and mupirocin.

The study identifies various AMR genes such as erm(A), erm(C), mupA, vga(A), and lnu(A) in methicillin-resistant coagulase-negative staphylococci (MRCoNS) from humans and pets, highlighting the prevalence of multidrug resistance and potential for interspecies transmission.

The study identified the presence of methicillin-resistant Staphylococcus aureus (MRSA) strains in cream-filled bakery products, with the mecA gene conferring resistance to oxacillin and the mupA gene conferring resistance to mupirocin. Additionally, the sea gene was found to be the predominant enterotoxin gene.

The study identified the presence of mecA, mupA, and qacA/B genes in Staphylococcus epidermidis isolates, which confer resistance to methicillin, mupirocin, and chlorhexidine, respectively. These genes were found in both clinical and colonized isolates, highlighting their importance in antimicrobial resistance.

The study identified several AMR genes in multidrug-resistant staphylococci from high-frequency touched surfaces in London, including blaZ, qacA/B, dfrC, norA, ant(4')-Ib, AAC(6')-Ie-APH(2")-Ia, fusB, msrA, ermC, mphC, tetK, mupA, cat, dfrG, lnuA, fusC, aph3-IIIa, sat4A, vgaA, and others. These genes conferred resistance to various antibiotics such as penicillin, fusidic acid, mupirocin, tetracycline, erythromycin, and chloramphenicol.

The study identified the mupA and aacA-aphD genes as responsible for mupirocin and gentamicin resistance, respectively, in the NICU outbreak clone of Staphylococcus aureus. These genes were part of the accessory genome and contributed to the distinct susceptibility profile of the outbreak strain.

The study identifies silenced antibiotic resistance genes in Staphylococcus aureus, highlighting the prevalence of transient antibiotic resistance due to mutations that inactivate resistance genes, leading to apparent susceptibility but potential re-emergence of resistance.

Three mupirocin-resistant Staphylococcus aureus isolates were identified, all carrying the mupA gene, indicating plasmid-mediated resistance.

The study identified mupA as the primary determinant of high-level mupirocin resistance and the ileS V588F mutation as the major cause of low-level resistance in Staphylococcus aureus isolates.

The study identifies the plasmid-mediated mupA gene as the primary cause of high-level mupirocin resistance (HLMR) in Gram-positive bacteria isolated from diseased companion animals. The mupA gene was detected in 17 HLMR strains, and its association with resistance was confirmed through PCR and sequencing analysis.

The study identified mupA as the primary gene responsible for high-level mupirocin resistance, and mutations in ileS (N213D and V588F) for low-level mupirocin resistance. Additionally, lsaE was found to contribute to retapamulin resistance.

The study identified high prevalence of multidrug-resistant ST239 isolates with strong biofilm-producing ability. Key AMR genes included mupA, fusC, erm(A), erm(C), ant(4')-Ia, aac(6')-Ie/aph(2''), aph(3')-IIIa, tetM, and tetK.

The study identified various AMR genes in MRSA isolates from Kuwait hospitals, including mupA, aacA-aphD, erm(A), erm(C), tet(K), tet(M), fusC, fusB, and faR1, which conferred resistance to mupirocin, gentamicin, erythromycin, tetracycline, and fusidic acid.

The study confirms that fusC mediates resistance to fusidic acid and mupA mediates high-level resistance to mupirocin in multiple S. aureus genetic backgrounds. Exposure to sub-inhibitory concentrations of these antibiotics leads to the selection of multidrug-resistant S. aureus strains.

The study presents a cross-resistance platform (CRP) consisting of 28 Staphylococcus aureus strains with defined resistance genotypes, designed to detect cross-resistance between established and novel antibacterial agents. The CRP includes various AMR genes and mutations that confer resistance to multiple antibiotic classes.

The study identified mupA and qacA/qacC genes as mediators of mupirocin and chlorhexidine resistance in MRSA isolates, highlighting the potential for plasmid-mediated spread of these resistance mechanisms.

The study identifies a mupirocin-resistant, methicillin-susceptible Staphylococcus aureus clone (ST121) associated with skin and soft tissue infections in Greece, carrying resistance genes mupA, fusB, and ant(4')-Ia.

The study identified various antimicrobial resistance genes in Staphylococcus aureus isolates from equids, including blaZ, mupA, lnuA, tetK, tetL, tetM, norA, dfrC, dfrG, dfrK, ermA, ermC, msrA, mphC, qacA/B, qacC, and fosB. An isolate (17-021) was found to carry the lnuA gene and mupA plasmid, conferring resistance to clindamycin and mupirocin. A mutation in the prs gene was associated with phenotypic susceptibility to β-lactam drugs in a mecA-positive isolate.

The study identified several AMR genes in MRSA ST113 strains, including aph(3')-IIIa, aad(6), sat-4, tet(K), mupA, and ant(4')-Ib, along with a point mutation in fusA conferring resistance to fusidic acid.

The study developed a lateral flow immunoassay for detecting Panton-Valentine leukocidin (PVL) in Staphylococcus aureus isolates from skin and soft tissue infections. The assay showed 100% sensitivity and specificity. The study also identified the presence of pvl genes and fusC, a fusidic acid resistance gene, in MRSA and MSSA isolates.

The study identified the mupA gene as the primary determinant of high-level mupirocin resistance in Staphylococcus aureus isolates from Iran. The gene was present in all HLMUPR strains and was associated with strong biofilm production.

The study characterizes various tetracycline and methicillin-resistant Staphylococcus aureus genetic lineages circulating in Spanish hospitals, identifying multiple AMR genes including blaZ, tetK, tetL, tetM, ermC, ermB, ant(4')-Ia, aac(6')-Ie-aph(2'')-Ia, mupA, and fusB.

The study reports the first methicillin-resistant, high-level mupirocin-resistant Staphylococcus argenteus isolate, which harbors the mupA gene on a plasmid and the blaZ gene on another plasmid.

The paper discusses the molecular mechanisms of drug resistance in Staphylococcus aureus, focusing on beta-lactam, glycopeptide, oxazolidinone, MLS-B, aminoglycoside, and other resistance mechanisms. Key genes identified include blaZ, mecA, mecC, vanA, cfr, ermA, ermC, aac(6')-Ib, aph(3')-IIIa, and aadD. Mutations in pbp2 and pbp2a were also found to contribute to resistance.

The study identified mupA and qacA genes associated with resistance to mupirocin and chlorhexidine, respectively, which could impact decolonization success in MRSA carriers.

The study identifies mupA as a gene conferring high-level mupirocin resistance in ST1898 MSSA clones, which were prevalent in the NICU and associated with decolonization efforts.

The study identified two novel sequence types (ST 7460 and ST 7635) of community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) in Kenya, carrying resistance genes for linezolid (cfr), mupirocin (mupA), and rifampin (rpoB).

The paper discusses the molecular mechanisms of resistance to non-beta-lactam antibiotics in Staphylococcus aureus, highlighting the roles of various genes and mutations in conferring resistance to macrolides, lincosamides, aminoglycosides, glycopeptides, oxazolidinones, lipopeptides, fluoroquinolones, and other antibiotics.

The study identified qacA/B and mupA genes as highly associated with resistance to chlorhexidine gluconate and mupirocin in Staphylococcus aureus isolates from school-age children in Guangzhou.

The study identified multiple AMR genes in the multidrug-resistant S. hominis ShoR14 isolate, including tetK, norA, aac(6')-aph(2"), aadD, blaZ, mecA, mupA, fusC, ermC, sul4, dfrC, and catA7, which contribute to resistance against various antibiotics.

The study identifies ileS mutations (V588F and V631F) and the mupA gene as key determinants of mupirocin resistance in MRSA isolates, particularly in ST764 clones.

The study identified several AMR genes in ST764-MRSA isolates, including ant(4')-Ib, aac(6')-aph(2"), aadD, mupA, qacB, and fosD, which conferred resistance to aminoglycosides, mupirocin, antiseptics, and fosfomycin. These findings highlight the diversity of resistance mechanisms in ST764-MRSA isolates.

The study identifies mecA and mupA as key antimicrobial resistance genes in chronic wound isolates of Staphylococcus epidermidis, along with qacA/qacB for resistance to quaternary ammonium compounds.

The study identifies vancomycin intermediate-resistant Staphylococcus haemolyticus SH-1 carrying multiple drug resistance genes and novel mutations in WalK gene associated with vancomycin resistance.

The study identified various antimicrobial resistance genes in Staphylococcus aureus strains derived from atopic dermatitis patients and healthy carriers, highlighting the presence of resistance to multiple antibiotics such as erythromycin, benzylpenicillin, and others.

The study identified several bacterial species, including Staphylococcus haemolyticus, Staphylococcus hominis, Staphylococcus epidermitis, Staphylococcus cohnii, Kocuria polaris, Arthrobacter agilis, and Deinococcus ficus, that exhibited resistance to specific antibiotics and UV radiation.

The study identified several antiseptic resistance genes (qacA/B, smr, qacG, qacH, qacJ), mupirocin resistance genes (mupA, mupB), and methicillin resistance gene (mecA) in coagulase-negative Staphylococcus (CoNS) isolates. High prevalence of antiseptic resistance was observed in CoNS isolates from healthcare workers, while antibiotic resistance was more prevalent in clinical infection samples.

The study identified various AMR genes including blaZ, mecA, erm(A), erm(C), erm(T), mph(C), msr(A), vga(A), lsaB, ant4′, aac6′-aph2″, tet(K), tet(M), dfrA, dfrG, catPC221, and mupA in CoNS isolates from healthy dogs and dog-owners. Additionally, a linezolid-resistant S. epidermidis isolate was found to have multiple amino acid substitutions in 50S ribosomal proteins L3 and L4.

The study identifies a mupirocin-resistant variant of the European epidemic fusidic acid-resistant impetigo clone of Staphylococcus aureus, which carries the mupA gene for mupirocin resistance and the fusB gene for fusidic acid resistance.

The study identified novel methicillin-resistant Staphylococcus pseudintermedius (MRSP) lineages, including ST726 and ST551, and characterized antimicrobial resistance genes such as mecA, blaZ, tetK, and mupA. It also noted a high prevalence of multidrug resistance (MDR) among MRSP isolates.

The study identifies several antibiotic resistance genes and mutations in Staphylococcus aureus isolates associated with increased resistance to methicillin, macrolides, and other antibiotics during the COVID-19 pandemic.

The study identifies AMR genes and mutations associated with the clonal replacement of MRSA strains in a Malaysian hospital, highlighting the role of desiccation tolerance and reduced antibiotic resistance.

The study identifies multi-drug resistant Staphylococcus epidermidis isolates from chronic wounds, particularly those carrying mecA and mupA genes, which confer resistance to methicillin and mupirocin, respectively. These isolates exhibit biofilm-forming capabilities and are associated with impaired wound healing.

The study identified several AMR genes in Staphylococcus pettenkoferi isolates from human and feline sources, including blaZ, mecA, ermA, tet(L), vanA, aph3-IIIa, ter(M), mupA, and fusB, which confer resistance to various antibiotics such as penicillins, methicillin, erythromycin, tetracyclines, vancomycin, gentamicin, mupirocin, and fusidic acid.

The study identified several antimicrobial resistance genes in MRSA isolates from patients with COVID-19 pneumonia and MRSA pneumonia without COVID-19, including aac(6')-aph(2''), aph(2'')-Ia, aph(3')-III, aadD, ermA, ermB, ermC, tetM, tetK, mupA, and tst. No significant differences in antimicrobial resistance genes were observed between the two groups.

The study identified methicillin-resistant S. aureus (MRSA) carrying the mecA gene, mupirocin-resistant S. aureus carrying the mupA gene, and fusidic acid-resistant S. aureus with novel point mutations in the fusA gene. Monolaurin was shown to inhibit these resistant strains without cytotoxicity.

The study identified several AMR genes in Staphylococcus saprophyticus strains isolated from humans and animals, including blaZ, mecA, ermA, ermB, tetM, fusB, and mupA, which confer resistance to various antibiotics such as beta-lactams, macrolides, tetracyclines, fusidic acid, and mupirocin.

The study identified several AMR genes in Staphylococcus aureus ST1 isolates from New Zealand, including blaZ, tet(38), mecA, mecR1, qacA, qacB, ermC, fusC, mupA, and others. These genes were associated with resistance to various antibiotics such as penicillin, tetracycline, methicillin, quaternary ammonium compounds, erythromycin, fusidic acid, mupirocin, and fluoroquinolones. The study also highlighted the presence of a novel prophage, φSabovST1, in bovine ST1 isolates, which encoded bovine-adapted leukocidins.

The study highlights increasing resistance to fusidic acid and mupirocin among MRSA and CoNS, with notable trends in erythromycin and ciprofloxacin resistance.