Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
efflux pump
Overview
Characterization of an Environmental Multidrug-Resistant Acinetobacter seifertii and Comparative Genomic Analysis Reveals Co-occurrence of Antimicrobial Resistance and Metal Tolerance Determinants.
The study characterizes an environmental multidrug-resistant Acinetobacter seifertii isolate (SAb133) and identifies multiple antimicrobial resistance genes, metal tolerance genes, and virulence factors. Key findings include the presence of bla ADC–25, bla TEM, and various efflux pump genes, along with metal tolerance genes and virulence factors.
Full pathogen characterisation: species identification including the detection of virulence factors and antibiotic resistance genes via multiplex DNA-assays.
The study presents a DNA microarray-based assay for the simultaneous detection of 44 sepsis-relevant bacterial pathogens, 360 virulence factors, and 409 antibiotic resistance genes. The assay was evaluated with 14 multidrug-resistant strains, including all ESKAPE pathogens.
Metagenome meta-analysis reveals an increase in the abundance of some multidrug efflux pumps and mobile genetic elements in chemically polluted environments.
The study found that chemical pollution, particularly petroleum pollution, increases the abundance of multidrug efflux pumps and certain beta-lactam resistance genes, while reducing the abundance of rifampicin resistance genes.
Genomic analysis of multidrug-resistant Delftia tsuruhatensis isolated from raw bovine milk.
The study identifies multiple efflux pump genes and a genus-specific OXA-926-like beta-lactamase in the multidrug-resistant Delftia tsuruhatensis strain MR-6/3H, contributing to resistance against various antibiotics.
Bacterial diversity and resistome analysis of drinking water stored in cisterns from two First Nations communities in Manitoba, Canada.
The study identified a diverse array of antimicrobial resistance genes in drinking water stored in cisterns from two First Nations communities in Manitoba, Canada. Key findings include the presence of genes such as aac(3')-Ia, aac(6')-Iia, aac(6')-Iic, aph(3')-Ia, acrD, smeB, smeR, FEZ-1, rm3, SPG-1, OXA-21, OXA-119, OXA-205, dfrA14, dfrB6, acrB, acrF, adeF, ceoB, emrA, mexE, mexF, mexI, oprN, oqxB, BRP(MBL), vanSO, axyY, CRP, efrB, macB, mexB, mexC, mexD, mexK, mexQ, mexW, mexY, mtrA, muxB, muxC, oleB, oleC, ompB, oprM, smeD, smeE, golS, mdsB, PER-2, TEM-126, msbA, arnA, bacA, bcrA, MCR-5, rosA, rosB, rpoB2, ugd, mexN, taeA, efpA, rphA, rphB, otr(A), otrC, tetA(48 ), ompH, and triC, which confer resistance to various antibiotics including aminoglycosides, beta-lactams, cephalosporins, carbapenems, fluoroquinolones, macrolides, monobactams, nitroimidazoles, peptides, phenicols, pleuromutilins, rifamycins, tetracyclines, and triclosan.
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