Browse AMR Genes

Explore antimicrobial resistance genes from the literature

nadB

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to nadB

Browse AMR rules for nadB

Overview

Drug Classes: sulfamethoxazole
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
G123D	-	-	-	sulfamethoxazole	Reslit	Candidate

Papers1

1

Epigenetic modifications and metabolic gene mutations drive resistance evolution in response to stimulatory antibiotics.

PMID 39820016 · 2025

Mutations in NadB were associated with resistance development.

Mutation Information

Protein Change: G123D
Confers Resistance To: sulfamethoxazole
Validation Method: site-directed mutagenesis and ZEP assay
Source Database: Reslit