narB

ionophore ABC transporter permease subunit NarB

Validation StatusConfirmed2+ DBs

Overview

Mechanism: Efflux pump
Validation Method: cloning and MIC testing
Drug Classes: MADURAMICIN, NARASIN, SALINOMYCIN, narasin, salinomycin, maduramicin
Organisms: Enterococcus faecium
Geographic Location: Norway
Papers: 1
Databases: Reference Gene CatalogResFinder DatabaseReslit

Papers1

PMID N/A

Gene Information

Gene Name: narB
Allele: NarB
Encodes: ionophore ABC transporter permease subunit NarB
Source Database: Reference Gene Catalog
Mechanism: Efflux pump
Confers Resistance To: MADURAMICINNARASINSALINOMYCIN
Organisms Tested In: • Enterococcus faecium
Sequence Accession: MN590304.1
Protein Accession: QHA94809.1
Notes: NarAB_permease subunit, only causes resistance if both NarB_1_MN590304 and NarA_1_MN590304 are present

PMID N/A

Gene Information

Gene Name: narB
Allele: NarB
Encodes: ionophore ABC transporter permease subunit NarB
Source Database: ResFinder Database
Mechanism: Efflux pump
Confers Resistance To: MADURAMICINNARASINSALINOMYCIN
Organisms Tested In: • Enterococcus faecium
Sequence Accession: MN590304.1
Protein Accession: QHA94809.1
Notes: NarAB_permease subunit, only causes resistance if both NarB_1_MN590304 and NarA_1_MN590304 are present

NarAB Is an ABC-Type Transporter That Confers Resistance to the Polyether Ionophores Narasin, Salinomycin, and Maduramicin, but Not Monensin.

PMID 32117133 · 2020

The study identifies the NarAB ABC-type transporter as the mechanism conferring resistance to narasin, salinomycin, and maduramicin in Enterococcus faecium, but not to monensin.

Gene Information

Gene Name: narB
Allele: NarB
Encodes: ABC-type transporter permease subunit
Source Database: Reslit
Confers Resistance To: narasinsalinomycinmaduramicin
Organisms Tested In: • Enterococcus faecium
Geographic Location: Norway
Validation Method: cloning and MIC testing
Sequence Accession: MN590304|MN590305|MN590306|MN590307|MN590308|MN590309|MN590310

NarAB Is an ABC-Type Transporter That Confers Resistance to the Polyether Ionophores Narasin, Salinomycin, and Maduramicin, but Not Monensin.

PMID 32117133 · 2020

Gene Information

Gene Name: narB
Allele: NarB
Source Database: ResFinder Database
Mechanism: Efflux pump
Confers Resistance To: MADURAMICINNARASINSALINOMYCIN
Organisms Tested In: • Enterococcus faecium
Sequence Accession: MN590304
Notes: NarAB_permease subunit, only causes resistance if both NarB_1_MN590304 and NarA_1_MN590304 are present

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narB

ionophore ABC transporter permease subunit NarB

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to narB

AMR Rules

Browse AMR rules for narB

Validation StatusConfirmed2+ DBs

Overview

Mechanism: Efflux pump
Validation Method: cloning and MIC testing
Drug Classes: MADURAMICIN, NARASIN, SALINOMYCIN, narasin, salinomycin, maduramicin
Organisms: Enterococcus faecium
Geographic Location: Norway
Papers: 1
Databases: Reference Gene CatalogResFinder DatabaseReslit

Papers1

PMID N/A

Gene Information

Gene Name: narB
Allele: NarB
Encodes: ionophore ABC transporter permease subunit NarB
Source Database: Reference Gene Catalog
Mechanism: Efflux pump
Confers Resistance To: MADURAMICINNARASINSALINOMYCIN
Organisms Tested In: • Enterococcus faecium
Sequence Accession: MN590304.1
Protein Accession: QHA94809.1
Notes: NarAB_permease subunit, only causes resistance if both NarB_1_MN590304 and NarA_1_MN590304 are present

PMID N/A

Gene Information

Gene Name: narB
Allele: NarB
Encodes: ionophore ABC transporter permease subunit NarB
Source Database: ResFinder Database
Mechanism: Efflux pump
Confers Resistance To: MADURAMICINNARASINSALINOMYCIN
Organisms Tested In: • Enterococcus faecium
Sequence Accession: MN590304.1
Protein Accession: QHA94809.1
Notes: NarAB_permease subunit, only causes resistance if both NarB_1_MN590304 and NarA_1_MN590304 are present

NarAB Is an ABC-Type Transporter That Confers Resistance to the Polyether Ionophores Narasin, Salinomycin, and Maduramicin, but Not Monensin.

PMID 32117133 · 2020

The study identifies the NarAB ABC-type transporter as the mechanism conferring resistance to narasin, salinomycin, and maduramicin in Enterococcus faecium, but not to monensin.

Gene Information

Gene Name: narB
Allele: NarB
Encodes: ABC-type transporter permease subunit
Source Database: Reslit
Confers Resistance To: narasinsalinomycinmaduramicin
Organisms Tested In: • Enterococcus faecium
Geographic Location: Norway
Validation Method: cloning and MIC testing
Sequence Accession: MN590304|MN590305|MN590306|MN590307|MN590308|MN590309|MN590310

NarAB Is an ABC-Type Transporter That Confers Resistance to the Polyether Ionophores Narasin, Salinomycin, and Maduramicin, but Not Monensin.

PMID 32117133 · 2020

Gene Information

Gene Name: narB
Allele: NarB
Source Database: ResFinder Database
Mechanism: Efflux pump
Confers Resistance To: MADURAMICINNARASINSALINOMYCIN
Organisms Tested In: • Enterococcus faecium
Sequence Accession: MN590304
Notes: NarAB_permease subunit, only causes resistance if both NarB_1_MN590304 and NarA_1_MN590304 are present

Comments (0)

No comments yet. Be the first to comment!

narB

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narB

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