nicT

View on PubMed

metal transporter

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to nicT

AMR Rules

Browse AMR rules for nicT

Validation StatusCandidate

Overview

Validation Method: MIC value increase and docking studies
Drug Classes: ofloxacin, gentamicin, norfloxacin, sparfloxacin, isoniazid, nalidixic acid
Organisms: Escherichia coli, Mycobacterium smegmatis
Papers: 1
Databases: Reslit

Papers1

Emerging antibiotic resistance by various novel proteins/enzymes.

PMID 40232578 · 2025

The paper discusses various novel proteins and enzymes involved in antibiotic resistance, highlighting mechanisms such as efflux pumps, antibiotic inactivation, and target modification. Specific genes like BON, CmeABC, NicT, AadT, SstFEG, and SA09310 were experimentally characterized for their roles in resistance.

Gene Information

Gene Name: nicT
Allele: NicT
Encodes: metal transporter
Source Database: Reslit
Confers Resistance To: ofloxacingentamicinnorfloxacinsparfloxacinisoniazidnalidixic acid
Organisms Tested In: • Escherichia coli
• Mycobacterium smegmatis
Validation Method: MIC value increase and docking studies

Comments (0)

No comments yet. Be the first to comment!

nicT

Gene Information

Browse AMR Genes

nicT

Gene Information