norV

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Anaerobic nitric oxide reductase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to norV

AMR Rules

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Validation StatusCandidate

Overview

Validation Method: differential protein expression analysis
Drug Classes: metronidazole
Organisms: Clostridioides difficile
Papers: 1
Databases: Reslit

Papers1

Impact of subinhibitory concentrations of metronidazole on proteome of Clostridioides difficile strains with different levels of susceptibility.

PMID 33166349 · 2020

The study identified that mutations in sigB and 630Δerm are associated with altered proteome and stress response to metronidazole in Clostridioides difficile strains.

Gene Information

Gene Name: norV
Allele: norV
Encodes: Anaerobic nitric oxide reductase
Source Database: Reslit
Confers Resistance To: metronidazole
Organisms Tested In: • Clostridioides difficile
Validation Method: differential protein expression analysis

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norV

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norV

Gene Information