Browse AMR Genes

Explore antimicrobial resistance genes from the literature

npr

Phosphorelay protein

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to npr

Browse AMR rules for npr

Overview

Drug Classes: kanamycin
Organisms: E. coli
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
L23R	-	-	E. coli	kanamycin	Reslit	Candidate

Papers1

1

Effects of a previously selected antibiotic resistance on mutations acquired during development of a second resistance in Escherichia coli.

PMID 30975082 · 2019

Mutation in npr was observed in wild-type E. coli adapted to kanamycin.

Mutation Information

Protein Change: L23R
Organisms: E. coli
Confers Resistance To: kanamycin
Validation Method: Whole genome sequencing and MIC measurements
Source Database: Reslit