Browse AMR Genes

Explore antimicrobial resistance genes from the literature

oatA

O-Acetyltransferase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to oatA

Browse AMR rules for oatA

Overview

Drug Classes: nafcillin
Organisms: Staphylococcus aureus
Papers: 1
Mutations: 4

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
G451S	-	-	Staphylococcus aureus	nafcillin	Reslit	Candidate
-	1239-1250del	-	Staphylococcus aureus	nafcillin	Reslit	Candidate
-	1327del	-	Staphylococcus aureus	nafcillin	Reslit	Candidate
-	29del	-	Staphylococcus aureus	nafcillin	Reslit	Candidate

Papers1

1

Genetic Determinants Enabling Medium-Dependent Adaptation to Nafcillin in Methicillin-Resistant Staphylococcus aureus.

PMID 32234776 · 2020

Mutation Information

oatA: p.G451S oatA: c.1239-1250del oatA: c.1327del oatA: c.29del

Protein Change: G451S
Nucleotide Change: 1239-1250del, 1327del, 29del
Organisms: Staphylococcus aureus
Confers Resistance To: nafcillin
Validation Method: whole-genome resequencing; whole-genome sequencing
Source Database: Reslit