Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
OleI family self-immunity macrolide glycosyltransferase
Overview
The crystal structure of two macrolide glycosyltransferases provides a blueprint for host cell antibiotic immunity.
The crystal structure of two macrolide glycosyltransferases provides a blueprint for host cell antibiotic immunity.
Intracellularly driven chemical modifications of antimicrobial secondary metabolites: Potent mechanisms of self-resistance.
The paper reviews various enzymatic modifications used by natural product (NP) producers to develop self-resistance against their own antimicrobial secondary metabolites, including phosphorylation, acylation, deglycosylation, glycosylation, redox reactions, hydrolysis, and dual modifications.
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