Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
outer membrane protein
Overview
| Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|
| P35A | - | - | - | ciprofloxacin|erythromycin|norfloxacin|novobiocin | Reslit | Candidate |
| M245T | - | - | - | ciprofloxacin|erythromycin|norfloxacin|novobiocin | Reslit | Candidate |
| S432N | - | - | - | ciprofloxacin|erythromycin|norfloxacin|novobiocin | Reslit | Candidate |
| L471I | - | - | - | ciprofloxacin|erythromycin|norfloxacin|novobiocin | Reslit | Candidate |
| L227I | - | - | - | carbapenems|aztreonam|cephalosporins | Reslit | Candidate |
| L250P | - | - | - | carbapenems|aztreonam|cephalosporins | Reslit | Candidate |
| A260S | - | - | - | carbapenems|aztreonam|cephalosporins | Reslit | Candidate |
| A275V | - | - | - | carbapenems|aztreonam|cephalosporins | Reslit | Candidate |
| Q343R | - | - | - | carbapenems|aztreonam|cephalosporins | Reslit | Candidate |
| V373A | - | - | - | carbapenems|aztreonam|cephalosporins | Reslit | Candidate |
| V382E | - | - | - | carbapenems|aztreonam|cephalosporins | Reslit | Candidate |
| D521N | - | - | - | carbapenems|aztreonam|cephalosporins | Reslit | Candidate |
Antibacterial Efficacy of Liposomal Formulations Containing Tobramycin and N-Acetylcysteine against Tobramycin-Resistant Escherichia coli, Klebsiella pneumoniae, and Acinetobacter baumannii.
The study identified various aminoglycoside-modifying enzymes (AMEs) and efflux pump genes contributing to tobramycin resistance in E. coli, K. pneumoniae, and A. baumannii. These genes include acc(3)-IIa, aac(6')-Ib-cr, ant(2")-Ia, aph(6)-Id, aph(3")-Ib, armA, rmtF, acrD, adeA, adeB, adeC, ompA, omp37, csgB, csgD, csgF, csgG, pgaA, pgaB, pgaC, pgaD, csuA, csuB, csuC, csuD, csuE, and bap.
Whole-genome sequencing of Alcaligenes sp. strain MMA: insight into the antibiotic and heavy metal resistant genes.
The study identified multiple antibiotic resistance genes in Alcaligenes sp. strain MMA, including those conferring resistance to fluoroquinolones, tetracyclines, beta-lactams, penams, and macrolides. Additionally, the strain exhibited resistance to multiple heavy metals such as Cd, Ni, Cu, and Zn.
Better together-Salmonella biofilm-associated antibiotic resistance.
The study identifies several genes involved in Salmonella biofilm-associated antibiotic resistance, including efflux pumps, porins, and stress response proteins, highlighting their role in multidrug resistance and biofilm formation.
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