Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
outer membrane porin
Overview
A Protein Important for Antimicrobial Peptide Resistance, YdeI/OmdA, Is in the Periplasm and Interacts with OmpD/NmpC.
The study identifies YdeI/OmdA, OmpD, YgiW, and OmpF as important for resistance to polymyxin B and cathelicidin antimicrobial peptide in Salmonella enterica serovar Typhimurium.
The expression levels of outer membrane proteins STM1530 and OmpD, which are influenced by the CpxAR and BaeSR two-component systems, play important roles in the ceftriaxone resistance of Salmonella enterica serovar Typhimurium.
The study identifies STM1530 and OmpD as outer membrane proteins involved in ceftriaxone resistance in Salmonella enterica serovar Typhimurium, with their expression influenced by the CpxAR and BaeSR two-component systems.
Role of OB-Fold Protein YdeI in Stress Response and Virulence of Salmonella enterica Serovar Enteritidis.
YdeI is a conserved membrane protein that plays a crucial role in protecting Salmonella enterica serovar Enteritidis against multiple stress conditions, including antimicrobial peptides, glucose and Mg2+ starvation, and bile stress. Deletion of ydeI leads to reduced survival, invasion, and virulence in S. Enteritidis.
The evolution of antibiotic resistance in an incurable and ultimately fatal infection: A retrospective case study.
The study identifies multiple mutations in genes such as ampD, deoR, wecA, rcsC, ompC, ompD, and phoE that contribute to antibiotic resistance in Enterobacter hormaechei. These mutations include transposon insertions, deletions, and frameshift variants, leading to resistance against β-lactams, carbapenems, and other antibiotics.
Carbapenem resistance in extensively drug-resistant Salmonella enterica serovar Agona and AmpC β-lactamase-producing S. Infantis.
The study identifies the loss of porins OmpC_378 and OmpD as critical for carbapenem resistance in Salmonella strains producing AmpC or ESBL β-lactamases. It also characterizes several beta-lactamase genes, including bla CTX-M-55, bla TEM-1B, and bla CMY-2, as well as the efflux pump regulatory gene ramAp.
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