ompP2

outer membrane porin

Overview

Mechanism: smaller channel conductance
Drug Classes: fluoroquinolones, ampicillin|penicillin|cephalothin
Organisms: Haemophilus influenzae
Papers: 2
Mutations: 2

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
T131K	-	-	Haemophilus influenzae	fluoroquinolones	Reslit	Candidate
V30I	-	smaller channel conductance	Haemophilus influenzae	ampicillin\|penicillin\|cephalothin	Reslit	Candidate

Papers2

In Vitro Derivation of Fluoroquinolone-Resistant Mutants from Multiple Lineages of Haemophilus influenzae and Identification of Mutations Associated with Fluoroquinolone Resistance.

PMID 31740553 · 2020

Mutation Information

ompP2: p.T131K

Protein Change: T131K
Organisms: Haemophilus influenzae
Confers Resistance To: fluoroquinolones
Validation Method: whole-genome sequencing
Source Database: Reslit

Variation in the composition and pore function of major outer membrane pore protein P2 of Haemophilus influenzae from cystic fibrosis patients.

PMID 9925510 · 1999

Mutation Information

ompP2: p.V30I

Protein Change: V30I
Organisms: Haemophilus influenzae
Confers Resistance To: ampicillin|penicillin|cephalothin
Effect on Function: smaller channel conductance
Validation Method: channel conductance measurement and MIC testing
Source Database: Reslit

ompP2

Mutations

Mutation Information

Mutation Information

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ompP2

Mutations

Mutation Information

Mutation Information