Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
General Bacterial Porin with reduced permeability to peptide antibiotics
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| Vcho_OmpT | Card Database | 1 | - | Vibrio cholerae | - | - | AF079766.2 | AAC28105.1 |
| ompT | Reslit | 2 | polymyxin b, aminoglycosides +1 | Vibrio cholerae O1 El Tor A1552 +1 | Northern Palestinian territories|Northern Palestine | 2013, 2024 | - | - |
Role of the Vibrio cholerae matrix protein Bap1 in cross-resistance to antimicrobial peptides.
The study identifies Bap1 and OmpT as critical factors in Vibrio cholerae's cross-resistance to antimicrobial peptides Polymyxin B and LL-37. Bap1 binds to OmpT on outer membrane vesicles (OMVs) and traps LL-37, reducing its effectiveness. OmpT's LDV domain is essential for Bap1 binding.
Molecular characterization of avian pathogenic Escherichia coli isolates from broiler farms in Northern Palestinian territories.
The study identified several virulence genes, including iroN, hlyF, iutA, tsh, iss, ompT, papGI, papGII, papC, and cva/cvi, which were associated with antibiotic resistance in APEC isolates from broiler farms in Northern Palestine. These genes were found to be prevalent among the isolates and correlated with resistance to multiple antibiotics.
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