ompV

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outer membrane protein

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

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UniProt

Protein entries specific to ompV

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Validation StatusCandidate

Overview

Mechanism: sensing antimicrobial peptides and activating the expression of multiple resistance systems
Validation Method: deletion mutant susceptibility testing
Drug Classes: polymyxin b
Organisms: Vibrio cholerae
Papers: 1
Databases: Reslit

Papers1

The carRS-ompV-virK operon of Vibrio cholerae senses antimicrobial peptides and activates the expression of multiple resistance systems.

PMID 40258937 · 2025

The study identifies ompV as a gene involved in polymyxin B resistance in Vibrio cholerae, showing that its deletion increases susceptibility to antimicrobial peptides.

Gene Information

Gene Name: ompV
Allele: ompV
Encodes: outer membrane protein
Source Database: Reslit
Mechanism: sensing antimicrobial peptides and activating the expression of multiple resistance systems
Confers Resistance To: polymyxin b
Organisms Tested In: • Vibrio cholerae
Validation Method: deletion mutant susceptibility testing

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ompV

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ompV

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