ompcf

View on PubMed

porin

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to ompcf

AMR Rules

Browse AMR rules for ompcf

Validation StatusCandidate

Overview

Validation Method: broth microdilution antimicrobial susceptibility testing (AST)
Drug Classes: chlorhexidine
Organisms: Escherichia coli
Papers: 1
Databases: Reslit

Papers1

Applying fluorescent dye assays to discriminate Escherichia coli chlorhexidine resistance phenotypes from porin and mlaA deletions and efflux pumps.

PMID 35840757 · 2022

The study characterizes the roles of mlaA, acrB, ompCF, and aceI in chlorhexidine resistance in E. coli through gene deletion mutants and plasmid transformants, demonstrating that these genes contribute to increased MIC values and altered membrane permeability.

Gene Information

Gene Name: ompcf
Allele: ompCF
Encodes: porin
Source Database: Reslit
Confers Resistance To: chlorhexidine
Organisms Tested In: • Escherichia coli
Validation Method: broth microdilution antimicrobial susceptibility testing (AST)

Comments (0)

No comments yet. Be the first to comment!

ompcf

Gene Information

Browse AMR Genes

ompcf

Gene Information