pbp1A

penicillin-binding protein 1A

Overview

Drug Classes: amoxicillin
Organisms: Helicobacter pylori
Papers: 1
Mutations: 2

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
T556S	A1666G	-	Helicobacter pylori	amoxicillin	Reslit	Candidate
N562Y	A1685G	-	Helicobacter pylori	amoxicillin	Reslit	Candidate

Papers1

Occurrence of Mutations in the Antimicrobial Target Genes Related to Levofloxacin, Clarithromycin, and Amoxicillin Resistance in Helicobacter pylori Isolates from Buenos Aires City.

PMID 27391421 · 2017

PBP-1A N562Y and/or T556S substitutions confer the AMX resistance in our isolates.

Mutation Information

pbp1A: p.T556S / c.A1666G pbp1A: p.N562Y / c.A1685G

Protein Change: T556S, N562Y
Nucleotide Change: A1666G, A1685G
Organisms: Helicobacter pylori
Confers Resistance To: amoxicillin
Validation Method: natural transformation
Source Database: Reslit

pbp1A

Mutations

Mutation Information

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pbp1A

Mutations

Mutation Information