Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
penicillin-binding protein PBP2M
Overview
Fatal Respiratory Diphtheria Caused by ß-Lactam-Resistant Corynebacterium diphtheriae.
Population genomics and antimicrobial resistance in Corynebacterium diphtheriae.
The study identifies several AMR genes in Corynebacterium diphtheriae, including pbp2m associated with penicillin resistance, ermX for macrolide resistance, and various genes for tetracycline, aminoglycoside, and sulfonamide resistance.
Corynebacterium diphtheriae Infections, South Africa, 2015-2023.
The study identifies the pbp2m gene as a determinant of penicillin resistance in Corynebacterium diphtheriae isolates, highlighting the importance of monitoring penicillin resistance in diphtheria treatment strategies.
Population structure and antimicrobial resistance of Corynebacterium diphtheriae in Victoria, Australia.
The study identified multiple AMR genes and mutations in contemporary Corynebacterium diphtheriae isolates from Victoria, Australia, including pbp2m, erm(X), aph(3')-Ia, aph(6)-Id, aph(3'')-Ib, tet(W), tet(33), tet(O), cmx, sul1, dfrA15, and mutations in gyrA and rpoB. These genes and mutations confer resistance to various antimicrobials such as penicillin, erythromycin, gentamicin, tetracycline, chloramphenicol, sulfamethoxazole, trimethoprim, ciprofloxacin, and rifampicin.
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