Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
penicillin-binding protein 2
Overview
| Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|
| A217T | - | - | Mycobacterium tuberculosis | amoxicillin|meropenem | Reslit | Candidate |
Role of penicillin-binding protein 2 (PBP2) in the antibiotic susceptibility and cell wall cross-linking of Staphylococcus aureus: evidence for the cooperative functioning of PBP2, PBP4, and PBP2A.
Selective Sweeps and Parallel Pathoadaptation Drive Pseudomonas aeruginosa Evolution in the Cystic Fibrosis Lung.
Uncovering Beta-Lactam Susceptibility Patterns in Clinical Isolates of Mycobacterium tuberculosis through Whole-Genome Sequencing.
The study identifies several genes and mutations associated with beta-lactam susceptibility in Mycobacterium tuberculosis, highlighting the role of specific genetic variations in influencing resistance patterns.
Pbp4 provides transpeptidase activity to the FtsW-PbpB peptidoglycan synthase to drive cephalosporin resistance in Enterococcus faecalis.
Pbp4 provides transpeptidase activity to the FtsW-PbpB peptidoglycan synthase, which is crucial for cephalosporin resistance in Enterococcus faecalis. PbpB and FtsW are required for this resistance mechanism, and Pbp4 interacts with both to maintain functionality under cephalosporin stress.
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