pdaA

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polysaccharide deacetylase

NCBI Pathogen Isolates

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NCBI Reference Gene Catalog

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UniProt

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Validation StatusCandidate

Overview

Validation Method: experimental validation through deletion mutant analysis and complementation
Drug Classes: polymyxins
Organisms: Legionella pneumophila
Papers: 1
Databases: Reslit

Papers1

Legionella pneumophila type II secretome reveals a polysaccharide deacetylase that impacts intracellular infection, biofilm formation, and resistance to polymyxin- and serum-mediated killing.

PMID 40539790 · 2025

The study identifies PdaA, a novel polysaccharide deacetylase in Legionella pneumophila, which contributes to resistance against polymyxin and serum-mediated killing.

Gene Information

Gene Name: pdaA
Allele: pdaA
Encodes: polysaccharide deacetylase
Source Database: Reslit
Confers Resistance To: polymyxins
Organisms Tested In: • Legionella pneumophila
Validation Method: experimental validation through deletion mutant analysis and complementation

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pdaA

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pdaA

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