pen_p_1

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penicillin acylase

NCBI Pathogen Isolates

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NCBI Reference Gene Catalog

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UniProt

Protein entries specific to pen_p_1

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Validation StatusCandidate

Overview

Validation Method: MIC testing
Drug Classes: penicillin
Organisms: Escherichia coli
Geographic Location: Canadian high Arctic
Papers: 1
Databases: Reslit

Papers1

Functional characterization of bacteria isolated from ancient arctic soil exposes diverse resistance mechanisms to modern antibiotics.

PMID 25807523 · 2015

The study identified eight unique resistance genes from ancient permafrost bacteria and ten from the active layer, showing resistance to aminoglycosides, β-lactams, and tetracyclines. Some genes conferred resistance to semi-synthetic antibiotics like amikacin.

Gene Information

Gene Name: pen_p_1
Allele: PEN_P_1
Encodes: penicillin acylase
Source Database: Reslit
Confers Resistance To: penicillin
Organisms Tested In: • Escherichia coli
Geographic Location: Canadian high Arctic
Validation Method: MIC testing
Sequence Accession: KP097117|KP097118|KP097119|KP097120|KP097121|KP097122|KP097123|KP097124|KP097125|KP097126|KP097127|KP097128|KP097129|KP097130|KP097131|KP097132|KP097133|KP097134|KP097135|KP097136

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pen_p_1

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pen_p_1

Gene Information