pena910

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penicillin-binding protein 2

NCBI Pathogen Isolates

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UniProt

Protein entries specific to pena910

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Validation StatusCandidate

Overview

Mechanism: mutation-induced resistance
Validation Method: antibiotic susceptibility testing and whole-genome sequencing
Drug Classes: penicillin
Organisms: Neisseria meningitidis
Geographic Location: Greece
Papers: 1
Databases: Reslit

Papers1

First report of meningococcal ciprofloxacin resistance in Greece due to invasive isolates of the sequence type ST-3129.

PMID 32621148 · 2020

The study reports the first ciprofloxacin-resistant Neisseria meningitidis isolates in Greece, belonging to sequence type ST-3129, carrying a novel gyrA allele (gyrA346) with T90I substitution and a new penA allele (penA910).

Gene Information

Gene Name: pena910
Allele: penA910
Encodes: penicillin-binding protein 2
Source Database: Reslit
Mechanism: mutation-induced resistance
Confers Resistance To: penicillin
Organisms Tested In: • Neisseria meningitidis
Geographic Location: Greece
Validation Method: antibiotic susceptibility testing and whole-genome sequencing
Sequence Accession: CP053425|CP053426

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pena910

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pena910

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