petC

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lipid A phosphoethanolamine transferase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to petC

AMR Rules

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Validation StatusCandidate

Overview

Validation Method: protein expression and colistin MIC assays
Drug Classes: colistin
Organisms: Escherichia coli
Geographic Location: United States
Papers: 1
Databases: Reslit

Papers1

Site-selective modifications by lipid A phosphoethanolamine transferases linked to colistin resistance and bacterial fitness.

PMID 39611852 · 2024

The study characterizes the functional diversity of lipid A phosphoethanolamine transferases (PETs) including mcr-1, mcr-3, mcr-9, eptA, petB, and petC, demonstrating their roles in colistin resistance and bacterial fitness in Escherichia coli.

Gene Information

Gene Name: petC
Allele: petC
Encodes: lipid A phosphoethanolamine transferase
Source Database: Reslit
Confers Resistance To: colistin
Organisms Tested In: • Escherichia coli
Geographic Location: United States
Validation Method: protein expression and colistin MIC assays
Sequence Accession: NZ_RWZM01000001.1|NZ_KI519076.1|NG_050417.1|NG_051171.1|NG_055505.1|NG_057470.1|NG_055658.1|NG_055781.1|NG_056413.1|NG_061399.1|MK070339.1|NG_066767.1|NC_000913.3|NZ_KX772778.1|SRX3031601

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petC

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petC

Gene Information