Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
6-phosphogluconolactonase
Overview
Metabolic reprogramming and flux to cell envelope precursors in a pentose phosphate pathway mutant increases MRSA resistance to β-lactam antibiotics.
Mutation of the pgl gene in MRSA increases resistance to β-lactam antibiotics, particularly oxacillin, through metabolic reprogramming and increased flux to cell envelope precursors. This resistance is dependent on the VraFG/GraRS complex.
Metabolic reprogramming and altered cell envelope characteristics in a pentose phosphate pathway mutant increases MRSA resistance to β-lactam antibiotics.
Mutation of the pgl gene in MRSA increases resistance to β-lactam antibiotics through metabolic reprogramming and altered cell envelope characteristics.
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