Browse AMR Genes

Explore antimicrobial resistance genes from the literature

pheS

phenylalanyl-tRNA synthase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to pheS

Browse AMR rules for pheS

Overview

Drug Classes: oxacillin, colistin
Organisms: Staphylococcus aureus, Mammaliicoccus sciuri, Acinetobacter baumannii
Papers: 3
Mutations: 4

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
F254S	-	-	Staphylococcus aureus, Mammaliicoccus sciuri	oxacillin	Reslit	Candidate
P2S	-	-	-	colistin	Reslit	Candidate
G94R	-	-	-	colistin	Reslit	Candidate
N138S	-	-	Acinetobacter baumannii	colistin	Reslit	Candidate

Papers3

1

Impact of the Stringent Stress Response on the Expression of Methicillin Resistance in Staphylococcaceae Strains Carrying mecA, mecA1 and mecC.

PMID 35203858 · 2022

Mutation Information

Protein Change: F254S
Organisms: Staphylococcus aureus, Mammaliicoccus sciuri
Confers Resistance To: oxacillin
Validation Method: whole-genome sequencing
Source Database: Reslit

2

Comparative genomics and molecular epidemiology of colistin-resistant Acinetobacter baumannii.

PMID 36659926 · 2023

Mutations in PheS were associated with colistin resistance.

Mutation Information

pheS: p.P2S pheS: p.G94R

Protein Change: P2S, G94R
Confers Resistance To: colistin
Validation Method: mutational analysis
Source Database: Reslit

3

The induction and identification of novel Colistin resistance mutations in Acinetobacter baumannii and their implications.

PMID 27329501 · 2016

Mutation in pheS was observed in BAL255-Day4.

Mutation Information

Protein Change: N138S
Organisms: Acinetobacter baumannii
Confers Resistance To: colistin
Validation Method: whole genome sequencing
Source Database: Reslit