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pldA

phospholipase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to pldA

Browse AMR rules for pldA

Overview

Mechanism: outer membrane disorganization
Drug Classes: colistin
Organisms: Acinetobacter baumannii
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
T200T	-	outer membrane disorganization	Acinetobacter baumannii	colistin	Reslit	Candidate

Papers1

1

Colistin Resistance in Acinetobacter baumannii: Molecular Mechanisms and Epidemiology.

PMID 36978383 · 2023

Mutation in pldA contributes to colistin resistance via outer membrane disorganization

Mutation Information

Protein Change: T200T
Organisms: Acinetobacter baumannii
Confers Resistance To: colistin
Effect on Function: outer membrane disorganization
Validation Method: reported in cited literature
Source Database: Reslit