Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
efflux pump
Overview
Detection of the epidemic Pseudomonas aeruginosa AUST-03 (ST242) strain in people with cystic fibrosis in South Africa.
The study identifies multidrug efflux pumps MexAB-OprM, MexCD-OprJ, MexEF-OprN, and MexXY-OprM as the primary resistance determinants in Pseudomonas aeruginosa AUST-03 isolates. Mutations in regulatory genes mexR, mexT, nalC, and nfxB contribute to the upregulation of these efflux pumps. Additionally, the study detects several antibiotic resistance genes, including crpP, blaOXA-50, blaOXA-1034, blaPDC-3, and blaPDC-374, which are associated with resistance to various antibiotics.
Acquired resistance of Stenotrophomonas maltophilia to antimicrobials induced by herbicide paraquat dichloride.
Exposure of Stenotrophomonas maltophilia to paraquat induces multidrug resistance through genetic mutations affecting efflux pumps, ribosomal proteins, and metabolic enzymes.
Essential oils modulate virulence phenotypes in a multidrug-resistant pyomelanogenic Pseudomonas aeruginosa clinical isolate.
The study identifies multiple AMR genes in the MDR P. aeruginosa strain U804, including beta-lactamases, aminoglycoside modifying enzymes, and efflux pumps, which contribute to its resistance against various antibiotics.
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